Circle of Willis Atherosclerosis Is a Risk Factor for Sporadic Alzheimer’s Disease

Circle of willis atherosclerosis is a risk factor for sporadic Alzheimer's disease.

OBJECTIVE We conducted a quantitative investigation of brain arterial atherosclerotic damage and its relationship to sporadic Alzheimer's disease (AD). METHODS AND RESULTS Fifty-four consecutive autopsy cases, 32 AD and 22 nondemented control subjects, were examined to establish the degree of arterial stenosis. Vessel external and lumenal area measurements were taken from 3-mm arterial cross-...

Human T Lymphotropic Virus Type I (HTLV-I) is a Risk Factor for Coronary Artery Disease

The circle of Willis.

On St Martin’s Day (November 11), volleys of gunpowder explosions disturb the quiet of Fenny Stratford, a small country town midway between Oxford and Cambridge close to Stony Stratford (1). The explosions are part of a curious celebration, which has taken place every year since 1734. The celebration consists of three events. The first is a sermon in the parish church for which the invited spea...

Anatomical Variations of Circle of Willis in 57 Human Brains

Purpose: The circle of willis is responsible for blood supply of brain, which may suffer from anatomical variations. These disturbances can lead to aneurysm or even arterial rupture. The purpose of this study was to evaluate the anatomical structure of the cerebral arteries forming the circle of willis in adult cadavers. Also, cerebral versus non- cerebral versus non-cerebral arterial walls wer...

paraoxonase is reduced in patients with growth hormone deficiency: a novel risk factor for atherosclerosis

background: growth hormone deficiency (ghd) is associated with an increased cardiovascular mortality.increased oxidative stress has been associated with development of cardiovascular and cerebrovascular diseases. in the present study, we aimed to evaluate oxidant and antioxidant status in patients with ghd by analyzing serum paraoxonase1 (pon1) activity, and malondialdehyde (mda) and thiol leve...